PSMD7 Rabbit Polyclonal Antibody (CAB5356)
- SKU:
- CAB5356
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PSMD7 Rabbit Polyclonal Antibody |
SKU: | CAB5356 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-324 of human PSMD7 (NP_002802.2). |
Sequence: | MPEL AVQK VVVH PLVL LSVV DHFN RIGK VGNQ KRVV GVLL GSWQ KKVL DVSN SFAV PFDE DDKD DSVW FLDH DYLE NMYG MFKK VNAR ERIV GWYH TGPK LHKN DIAI NELM KRYC PNSV LVII DVKP KDLG LPTE AYIS VEEV HDDG TPTS KTFE HVTS EIGA EEAE EVGV EHLL RDIK DTTV GTLS QRIT NQVH GLKG LNSK LLDI RSYL EKVA TGKL PINH QIIY QLQD VFNL LPDV SLQE FVKA FYLK TNDQ MVVV YLAS LIRS VVAL HNLI NNKI ANRD AEKK EGQE KEES KKDR KEDK EKDK DKEK SDVK KEEK KEKK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | P40; S12; Rpn8; MOV34; PSMD7 |
Positive Sample: | MCF7,SW620,A-549,K-562,BT-474,Mouse skeletal muscle,Mouse heart,Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular exosome, extracellular region, nucleoplasm, nucleus |
Calculated MW: | 37kDa |
Observed MW: | 37kDa |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17.
Purification Method: | Affinity purification |
Gene ID: | 5713 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |