The PSMD6 Polyclonal Antibody (CAB18263) is a valuable tool for researchers studying the PSMD6 protein, a subunit of the 26S proteasome involved in protein degradation and cell regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications. By specifically binding to the PSMD6 protein, researchers can detect and analyze its expression in various cell types, making it an essential reagent for studies in cell biology and protein degradation pathways.PSMD6 plays a crucial role in maintaining cellular homeostasis by regulating the degradation of damaged or unwanted proteins, thereby influencing cell growth, division, and response to stress.
Dysregulation of PSMD6 has been associated with various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Understanding the function of PSMD6 is essential for developing targeted therapies for these diseases and uncovering novel pathways for therapeutic intervention.Overall, the PSMD6 Polyclonal Antibody is a reliable tool for researchers investigating the role of PSMD6 in cellular processes and disease pathogenesis. Its high specificity and sensitivity make it an excellent choice for studies aiming to elucidate the mechanisms of protein degradation and identify novel targets for therapeutic development.
Product Name:
PSMD6 Rabbit Polyclonal Antibody
SKU:
CAB18263
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-307 of human PSMD6 (NP_055629.1).
This gene encodes a member of the protease subunit S10 family. The encoded protein is a subunit of the 26S proteasome which colocalizes with DNA damage foci and is involved in the ATP-dependent degradation of ubiquinated proteins. Alternative splicing results in multiple transcript variants
Purification Method:
Affinity purification
Gene ID:
9861
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PSMD6 Rabbit pAb (CAB18263) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
