The PSMD14 Rabbit Monoclonal Antibody (CAB9608) is a valuable tool for researchers studying the PSMD14 protein, a key component of the 26S proteasome complex involved in protein degradation and regulation. This antibody, developed using rabbit monoclonal technology, exhibits high specificity and sensitivity towards human samples, making it ideal for use in various biochemical and cell biology assays.PSMD14, also known as Rpn11, is essential for maintaining cellular homeostasis by regulating protein turnover and degradation. Dysregulation of the proteasome system, including PSMD14, has been implicated in various diseases such as cancer, neurodegenerative disorders, and autoimmune conditions.
By targeting PSMD14 with this antibody, researchers can investigate its role in disease pathogenesis and potentially identify novel therapeutic targets for intervention.This PSMD14 Rabbit Monoclonal Antibody is validated for use in immunohistochemistry, immunofluorescence, and other protein detection techniques, providing researchers with a reliable tool for studying the function and localization of PSMD14 in different cellular contexts. With its high specificity and sensitivity, this antibody is a valuable asset for research in areas such as cancer biology, cell signaling, and drug discovery.
Product Name:
PSMD14 Rabbit Monoclonal Antibody
SKU:
CAB9608
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 112-210 of human PSMD14 (O00487).
This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.
Purification Method:
Affinity purification
Gene ID:
10213
Clone Number:
ARC1655
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using PSMD14 Rabbit mAb (CAB9608) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
