The PSMD14 Polyclonal Antibody (CAB10782) is a powerful tool for researchers studying the PSMD14 protein, which is a subunit of the 26S proteasome complex involved in protein degradation. This antibody, produced in rabbits, shows high reactivity with human samples and is validated for use in Western blotting applications. By specifically binding to the PSMD14 protein, researchers can accurately detect and analyze its expression in a variety of cell types.PSMD14 plays a crucial role in maintaining cellular homeostasis by regulating the degradation of proteins involved in various cellular processes. Dysregulation of the proteasome system, including PSMD14, has been implicated in diseases such as cancer, neurodegenerative disorders, and autoimmune conditions.
Therefore, studying the function of PSMD14 using this antibody can provide valuable insights into disease mechanisms and potential therapeutic targets.Overall, the PSMD14 Polyclonal Antibody (CAB10782) is an essential tool for researchers interested in unraveling the role of PSMD14 in cellular processes and disease pathogenesis. Its high specificity and reliability make it an ideal choice for studies in molecular biology, biochemistry, and drug discovery.
Product Name:
PSMD14 Rabbit Polyclonal Antibody
SKU:
CAB10782
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 160-300 of human PSMD14 (NP_005796.1).
This gene encodes a component of the 26S proteasome. The 26S proteasome is a large multiprotein complex that catalyzes the degradation of ubiquitinated intracellular proteins. The encoded protein is a component of the 19S regulatory cap complex of the 26S proteasome and mediates substrate deubiquitination. A pseudogene of this gene is also located on the long arm of chromosome 2.
Purification Method:
Affinity purification
Gene ID:
10213
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PSMD14 Rabbit pAb (CAB10782) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
