PSMD13 Rabbit Polyclonal Antibody (CAB6956)
- SKU:
- CAB6956
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PSMD13 Rabbit Polyclonal Antibody |
SKU: | CAB6956 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-250 of human PSMD13 (NP_002808.3). |
Sequence: | MKDV PGFL QQSQ NSGP GQPA VWHR LEEL YTKK LWHQ LTLQ VLDF VQDP CFAQ GDGL IKLY ENFI SEFE HRVN PLSL VEII LHVV RQMT DPNV ALTF LEKT REKV KSSD EAVI LCKT AIGA LKLN IGDL QVTK ETIE DVEE MLNN LPGV TSVH SRFY DLSS KYYQ TIGN HASY YKDA LRFL GCVD IKDL PVSE QQER AFTL GLAG LLGE GVFN FGEL LMHP VLES LRNT DRQW LIDT LYAF NSGN VERF QT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | S11; Rpn9; p40.5; HSPC027; PSMD13 |
Positive Sample: | HeLa,HepG2,Jurkat,HL-60,SW620,Mouse testis,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | cytosol, extracellular region, nucleoplasm, nucleus |
Calculated MW: | 43kDa |
Observed MW: | 43kDa |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.
Purification Method: | Affinity purification |
Gene ID: | 5719 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |