PSMD11 Rabbit Polyclonal Antibody (CAB15306)
- SKU:
- CAB15306
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PSMD11 Rabbit Polyclonal Antibody |
SKU: | CAB15306 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 253-422 of human PSMD11 (NP_002806.2). |
Sequence: | YMLL CKIM LNTP EDVQ ALVS GKLA LRYA GRQT EALK CVAQ ASKN RSLA DFEK ALTD YRAE LRDD PIIS THLA KLYD NLLE QNLI RVIE PFSR VQIE HISS LIKL SKAD VERK LSQM ILDK KFHG ILDQ GEGV LIIF DEPP VDKT YEAA LETI QNMS KVVD SLYN KAKK LT |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:1000 - 1:5000 IF/ICC,1:50 - 1:200 |
Synonyms: | S9; Rpn6; p44.5; PSMD11 |
Positive Sample: | NCI-H460,293T,Mouse brain,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, cytosol. |
Calculated MW: | 47kDa |
Observed MW: | 47kDa |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the proteasome subunit S9 family that functions as a non-ATPase subunit of the 19S regulator and is phosphorylated by AMP-activated protein kinase. Alternatively spliced transcript variants have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5717 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |