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PSMD11 PAT2C7AT Monoclonal Antibody [PAT2C7AT] (CPAB0248)

SKU:
CPAB0248
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT2C7AT
Applications:
WB
ELISA
FC
€149
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Description

system_update_alt Datasheet

PSMD11 PAT2C7AT Monoclonal Antibody [PAT2C7AT] (CPAB0248)

The PSMD11 Polyclonal Antibody (CPAB0248) is a valuable tool for researchers studying the PSMD11 protein, which is a subunit of the 26S proteasome complex involved in protein degradation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications.PSMD11 is essential for the proper functioning of the proteasome, a critical component of cellular protein regulation and turnover. Dysregulation of PSMD11 has been implicated in various diseases, including cancer and neurodegenerative disorders.

By targeting PSMD11 with this antibody, researchers can investigate its role in disease pathology and potential therapeutic interventions.Overall, the PSMD11 Polyclonal Antibody (CPAB0248) is a reliable tool for studying the function and regulation of the PSMD11 protein, offering insights into its roles in cellular processes and disease mechanisms.

Product Name:PSMD11 PAT2C7AT Antibody
Product Sku:CPAB0248
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PSMD11 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human PSMD11 PAT2C7AT amino acids 1-422 purified from Ecoli.
Clone:PAT2C7AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:PSMD11 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:The 26S proteasome is a multicatalytic proteinase complex with a well ordered structure composed of two complexes- a 20S core and a 19S regulator. PSMD11 is a non-ATPase subunit of the 19S regulator. The 20S core is composed of four rings of 28 non-identical subunits; two rings are composed of 7 alpha subunits and two rings are composed of 7 beta subunits. The 19S regulator is composed of a base that contains six ATPase subunits and two non-ATPase subunits, and a lid that contains up to ten non-ATPase subunits. Proteasomes are spread throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An indispensable function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides.
Synonyms:26S proteasome non-ATPase regulatory subunit 11, 26S proteasome regulatory subunit S9, 26S proteasome regulatory subunit RPN6, 26S proteasome regulatory subunit p44.5, PSMD11, S9, Rpn6, p44.5, MGC3844.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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