The PSMD10 Polyclonal Antibody (CAB1949) is a valuable tool for researchers studying the PSMD10 protein, also known as the 26S proteasome non-ATPase regulatory subunit 10. This antibody, generated in rabbits, exhibits high specificity and reactivity with human samples, making it ideal for use in Western blot applications.PSMD10 is a crucial component of the 26S proteasome, a complex involved in protein degradation and turnover. Dysregulation of the proteasome pathway has been implicated in various diseases, particularly cancer.
The PSMD10 protein has been shown to play a role in cell cycle progression and apoptosis, making it a potential target for cancer therapy.By utilizing the PSMD10 Polyclonal Antibody, researchers can detect and analyze the PSMD10 protein in different cell types and investigate its function in various biological processes. This antibody is a valuable tool for studies in cancer research, molecular biology, and cell biology, providing insights into the role of PSMD10 in disease development and progression.
Product Name:
PSMD10 Rabbit Polyclonal Antibody
SKU:
CAB1949
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-226 of human PSMD10 (NP_002805.1).
This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.
Purification Method:
Affinity purification
Gene ID:
5716
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from SW620 cells, using PSMD10 Rabbit pAb (CAB1949) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
