PSMC6 Rabbit Polyclonal Antibody (CAB5377)
- SKU:
- CAB5377
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Description
Product Name: | PSMC6 Rabbit Polyclonal Antibody |
SKU: | CAB5377 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-150 of human PSMC6 (NP_002797.3). |
Sequence: | DKAL QDYR KKLL EHKE IDGR LKEL REQL KELT KQYE KSEN DLKA LQSV GQIV GEVL KQLT EEKF IVKA TNGP RYVV GCRR QLDK SKLK PGTR VALD MTTL TIMR YLPR EVDP LVYN MSHE DPGN VSYS EIG |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | p42; RPT5; SUG2; PSMC6 |
Positive Sample: | NCI-H460,293T,SH-SY5Y,Mouse liver,Mouse kidney,Mouse brain,Mouse heart,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 44kDa |
Observed MW: | 45kDa |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.
Purification Method: | Affinity purification |
Gene ID: | 5706 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |