PSMB9/LMP2 Rabbit Polyclonal Antibody (CAB1771)
- SKU:
- CAB1771
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | PSMB9/LMP2 Rabbit Polyclonal Antibody |
SKU: | CAB1771 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-219 of human PSMB9/LMP2 (NP_002791.1). |
Sequence: | MLRA GAPT GDLP RAGE VHTG TTIM AVEF DGGV VMGS DSRV SAGE AVVN RVFD KLSP LHER IYCA LSGS AADA QAVA DMAA YQLE LHGI ELEE PPLV LAAA NVVR NISY KYRE DLSA HLMV AGWD QREG GQVY GTLG GMLT RQPF AIGG SGST FIYG YVDA AYKP GMSP EECR RFTT DAIA LAMS RDGS SGGV IYLV TITA AGVD HRVI LGNE LPKF YDE |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:10 - 1:100 |
Synonyms: | LMP2; PRAAS3; PSMB6i; RING12; beta1i; PSMB9/LMP2 |
Positive Sample: | Raji,THP-1 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. This gene is located in the class II region of the MHC (major histocompatibility complex). Expression of this gene is induced by gamma interferon and this gene product replaces catalytic subunit 1 (proteasome beta 6 subunit) in the immunoproteasome. Proteolytic processing is required to generate a mature subunit.
Purification Method: | Affinity purification |
Gene ID: | 5698 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |