PSMB5 Rabbit Polyclonal Antibody (CAB1975)
- SKU:
- CAB1975
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | PSMB5 Rabbit Polyclonal Antibody |
SKU: | CAB1975 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-263 of human PSMB5 (NP_002788.1). |
Sequence: | MALA SVLE RPLP VNQR GFFG LGGR ADLL DLGP GSLS DGLS LAAP GWGV PEEP GIEM LHGT TTLA FKFR HGVI VAAD SRAT AGAY IASQ TVKK VIEI NPYL LGTM AGGA ADCS FWER LLAR QCRI YELR NKER ISVA AASK LLAN MVYQ YKGM GLSM GTMI CGWD KRGP GLYY VDSE GNRI SGAT FSVG SGSV YAYG VMDR GYSY DLEV EQAY DLAR RAIY QATY RDAY SGGA VNLY HVRE DGWI RVSS DNVA DLHE KYSG STP |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:2000 - 1:7000 IHC-P,1:500 - 1:1000 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | MB1; LMPX; PSMB5 |
Positive Sample: | MCF7,HeLa |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 28kDa |
Observed MW: | 22kDa/28kDa |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit in the proteasome. This catalytic subunit is not present in the immunoproteasome and is replaced by catalytic subunit 3i (proteasome beta 8 subunit). Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5693 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |