PSMB3 Rabbit Polyclonal Antibody (CAB9947)
- SKU:
- CAB9947
- Product Type:
- Antibody
- Applications:
- WB
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | PSMB3 Rabbit Polyclonal Antibody |
SKU: | CAB9947 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-205 of human PSMB3 (NP_002786.2). |
Sequence: | MSIM SYNG GAVM AMKG KNCV AIAA DRRF GIQA QMVT TDFQ KIFP MGDR LYIG LAGL ATDV QTVA QRLK FRLN LYEL KEGR QIKP YTLM SMVA NLLY EKRF GPYY TEPV IAGL DPKT FKPF ICSL DLIG CPMV TDDF VVSG TCAE QMYG MCES LWEP NMDP DHLF ETIS QAML NAVD RDAV SGMG VIVH IIEK DKIT TRTL KARM D |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 |
Synonyms: | HC10-II; PSMB3 |
Positive Sample: | NIH/3T3,MCF7,HeLa,Jurkat,Mouse brain,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants
Purification Method: | Affinity purification |
Gene ID: | 5691 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |