The PSMB2 Polyclonal Antibody (CAB5483) is a valuable tool for researchers studying the proteasome subunit beta type-2 (PSMB2) protein. This antibody is produced in rabbits and is highly reactive with human samples, making it ideal for Western blot applications. By binding specifically to the PSMB2 protein, this antibody enables accurate detection and analysis in a variety of cell types.The PSMB2 protein is a crucial component of the proteasome complex, responsible for degrading unwanted or damaged proteins in the cell. Research into the function and regulation of PSMB2 is important for understanding cellular processes related to protein degradation, cell cycle control, and immune response.
The PSMB2 Polyclonal Antibody is a valuable tool for investigating these processes in the context of cancer, neurodegenerative diseases, and autoimmune disorders.By using the PSMB2 Polyclonal Antibody in their research, scientists can gain insights into the role of this essential protein in health and disease, paving the way for the development of targeted therapies and treatments.
Product Name:
PSMB2 Rabbit Polyclonal Antibody
SKU:
CAB5483
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PSMB2 (NP_002785.1).
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5690
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PSMB2 Rabbit pAb (CAB5483) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
