PSMB2 Rabbit Polyclonal Antibody (CAB13630)
- SKU:
- CAB13630
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | PSMB2 Rabbit Polyclonal Antibody |
SKU: | CAB13630 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-201 of human PSMB2 (NP_002785.1). |
Sequence: | MEYL IGIQ GPDY VLVA SDRV AASN IVQM KDDH DKMF KMSE KILL LCVG EAGD TVQF AEYI QKNV QLYK MRNG YELS PTAA ANFT RRNL ADCL RSRT PYHV NLLL AGYD EHEG PALY YMDY LAAL AKAP FAAH GYGA FLTL SILD RYYT PTIS RERA VELL RKCL EELQ KRFI LNLP TFSV RIID KNGI HDLD NISF PKQG S |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | HC7-I; PSMB2 |
Positive Sample: | 22Rv1,U-937,K-562,U-87MG,HT-29,HeLa,A673,BT-474 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 23kDa |
Observed MW: | 23kDa |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 5690 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |