PSMB10 Rabbit Polyclonal Antibody (CAB5452)
- SKU:
- CAB5452
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Immunology
Description
Product Name: | PSMB10 Rabbit Polyclonal Antibody |
SKU: | CAB5452 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-273 of human PSMB10 (NP_002792.1). |
Sequence: | MLKP ALEP RGGF SFEN CQRN ASLE RVLP GLKV PHAR KTGT TIAG LVFQ DGVI LGAD TRAT NDSV VADK SCEK IHFI APKI YCCG AGVA ADAE MTTR MVAS KMEL HALS TGRE PRVA TVTR ILRQ TLFR YQGH VGAS LIVG GVDL TGPQ LYGV HPHG SYSR LPFT ALGS GQDA ALAV LEDR FQPN MTLE AAQG LLVE AVTA GILG DLGS GGNV DACV ITKT GAKL LRTL SSPT EPVK RSGR YHFV PGTT AVLT QTVK PLTL ELVE ETVQ AMEV E |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:100 |
Synonyms: | LMP10; MECL1; PRAAS5; beta2i; PSMB10 |
Positive Sample: | THP-1 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 29kDa |
Observed MW: | 29kDa |
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.
Purification Method: | Affinity purification |
Gene ID: | 5699 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |