PSMA7 Rabbit Polyclonal Antibody (CAB4052)
- SKU:
- CAB4052
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Immunology
Description
Product Name: | PSMA7 Rabbit Polyclonal Antibody |
SKU: | CAB4052 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-248 of human PSMA7 (NP_002783.1). |
Sequence: | MSYD RAIT VFSP DGHL FQVE YAQE AVKK GSTA VGVR GRDI VVLG VEKK SVAK LQDE RTVR KICA LDDN VCMA FAGL TADA RIVI NRAR VECQ SHRL TVED PVTV EYIT RYIA SLKQ RYTQ SNGR RPFG ISAL IVGF DFDG TPRL YQTD PSGT YHAW KANA IGRG AKSV REFL EKNY TDEA IETD DLTI KLVI KALL EVVQ SGGK NIEL AVMR RDQS LKIL NPEE IEKY VAEI EKEK EENE KKKQ KKAS |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | C6; HSPC; RC6-1; XAPC7; HEL-S-276; PSMA7 |
Positive Sample: | U-87MG,293T,MCF7,Mouse brain,Mouse liver,Mouse lung,Rat liver |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus. |
Calculated MW: | 28kDa |
Observed MW: | 30kDa |
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the peptidase T1A family that functions as a 20S core alpha subunit. The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity, an activity essential for viral replication. The encoded protein also plays a role in the cellular stress response by regulating hypoxia-inducible factor-1alpha. A pseudogene of this gene is located on the long arm of chromosome 9.
Purification Method: | Affinity purification |
Gene ID: | 5688 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |