The PSMA2 Rabbit Monoclonal Antibody (CAB9182) is a valuable tool for research focused on PSMA2, a subunit of the proteasome complex involved in protein degradation. This antibody, developed using rabbit monoclonal technology, exhibits high reactivity with human samples and has been validated for use in Western blot applications.PSMA2 plays a crucial role in maintaining cellular homeostasis by degrading proteins that are damaged or no longer needed. Dysregulation of the proteasome complex, including PSMA2, has been implicated in various diseases such as cancer, neurodegenerative disorders, and autoimmune conditions.
Therefore, studying the expression and activity of PSMA2 using this antibody can provide valuable insights into disease mechanisms and potential therapeutic targets.With its specificity and sensitivity in detecting PSMA2 protein levels, this monoclonal antibody is an essential tool for researchers in the fields of cell biology, molecular biology, and protein degradation pathways. By enabling precise detection and analysis of PSMA2 expression in various cell types, this antibody contributes to advancing our understanding of cellular processes and disease pathology.
Product Name:
PSMA2 Rabbit Monoclonal Antibody
SKU:
CAB9182
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-100 of human PSMA2 (P25787).
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
Purification Method:
Affinity purification
Gene ID:
5683
Clone Number:
ARC1465
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using PSMA2 Rabbit mAb (CAB9182) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
