The PSMA2 Polyclonal Antibody (CAB2504) is a vital tool for researchers studying PSMA2, a proteasome subunit involved in protein degradation. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it an ideal choice for Western blot applications. By specifically binding to the PSMA2 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it a valuable tool for studies in molecular biology and cancer research.PSMA2, a key component of the proteasome complex, plays a crucial role in regulating protein turnover and maintaining cellular homeostasis.
Dysregulation of PSMA2 has been implicated in various diseases, including cancer and neurodegenerative disorders. By studying the function of PSMA2, researchers can gain insights into its role in disease development and potentially identify new therapeutic targets.Overall, the PSMA2 Polyclonal Antibody (CAB2504) is a valuable asset for researchers investigating the function of PSMA2 and its implications in disease pathology. Its high specificity and reactivity make it a reliable tool for advancing our understanding of proteasome biology and its relevance to human health.
Product Name:
PSMA2 Rabbit Polyclonal Antibody
SKU:
CAB2504
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-234 of human PSMA2 (NP_002778.1).
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit.
Purification Method:
Affinity purification
Gene ID:
5683
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PSMA2 Rabbit pAb (CAB2504) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
