The PSIP1 Polyclonal Antibody (CAB14852) is a valuable tool for researchers studying PSIP1, a protein involved in various cellular processes including transcriptional regulation and chromatin organization. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PSIP1 protein, researchers can accurately detect and analyze its expression in different cell types, making it ideal for studies in molecular biology and cancer research.
PSIP1, also known as LEDGF/p75, plays a crucial role in HIV replication and integration, making it an important target for antiviral drug development. Additionally, PSIP1 has been implicated in various cancers and neurological disorders, highlighting its significance in disease progression and potential therapeutic interventions. By further exploring the function of PSIP1, researchers can gain valuable insights into disease mechanisms and potentially identify new treatment strategies.
Product Name:
PSIP1 Rabbit Polyclonal Antibody
SKU:
CAB14852
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2).
Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription coactivator activity. Involved in mRNA 5'-splice site recognition and positive regulation of transcription by RNA polymerase II. Located in heterochromatin; nuclear periphery; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
11168
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using PSIP1 antibody (CAB14852) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
