The PSIP1 Polyclonal Antibody is a valuable tool for researchers studying PSIP1, also known as lens epithelium-derived growth factor (LEDGF/p75), a protein involved in chromatin tethering and transcriptional regulation. This antibody, generated in rabbits, is highly specific for detecting PSIP1 in human samples and has been validated for use in Western blot applications.PSIP1 plays a crucial role in HIV integration and has been implicated in various diseases, including cancer and neurodegenerative disorders.
By targeting PSIP1 with this antibody, researchers can investigate its function in chromatin organization and gene expression, providing insights into the molecular mechanisms underlying these diseases.Whether studying HIV infection, gene regulation, or disease pathology, the PSIP1 Polyclonal Antibody offers researchers a reliable tool for detecting and analyzing PSIP1 in a variety of experimental settings.
Product Name:
PSIP1 Polyclonal Antibody
SKU:
CAB21350
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 301-530 of human PSIP1 (NP_150091.2).
Enables DNA-binding transcription factor binding activity; chromatin binding activity; and transcription coactivator activity. Involved in mRNA 5'-splice site recognition and positive regulation of transcription by RNA polymerase II. Located in heterochromatin; nuclear periphery; and nucleoplasm.
Purification Method:
Affinity purification
Gene ID:
11168
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PSIP1 Rabbit pAb (CAB21350) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
