PSG6 Antibody (PACO29224)
- SKU:
- PACO29224
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
PSG6 Antibody (PACO29224)
The PSG6 Polyclonal Antibody (PAC03224) is a valuable tool for researchers studying PSG6, a cell surface protein involved in immune regulation and pregnancy-related processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By targeting the PSG6 protein, researchers can accurately detect and analyze its expression in various cell types, making it an essential asset for studies in immunology and reproductive biology.PSG6, also known as pregnancy-specific glycoprotein 6, is known for its role in promoting immune tolerance during pregnancy and modulating the maternal immune response to support fetal development.
Its involvement in these processes highlights its significance in reproductive health and immune regulation. Researchers exploring the functions of PSG6 can gain valuable insights into pregnancy-related disorders, immune-related complications in pregnancy, and potential therapeutic interventions targeting this protein.Overall, the PSG6 Polyclonal Antibody is a reliable tool for investigating the roles of PSG6 in immune regulation and pregnancy, paving the way for advancements in reproductive health research and the development of novel interventions for pregnancy-related disorders.
| Antibody Name: | PSG6 Antibody (PACO29224) |
| Antibody SKU: | PACO29224 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human Pregnancy-specific beta-1-glycoprotein 6 protein (35-300AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: PSG6 antibody at 6µg/ml Lane 1: HepG2 whole cell lysate Lane 2: 293T whole cell lysate Lane 3: MCF-7 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 49, 48 kDa Observed band size: 49 kDa . |
| Background: | extracellular region, female pregnancy |
| Synonyms: | Pregnancy-specific beta-1-glycoprotein 6 (PS-beta-G-6) (PSBG-6) (Pregnancy-specific glycoprotein 6) (Pregnancy-specific beta-1-glycoprotein 10) (PS-beta-G-10) (PSBG-10) (Pregnancy-specific glycoprotein 10) (Pregnancy-specific beta-1-glycoprotein 12) (PS-beta-G-12) (PSBG-12) (Pregnancy-specific glycoprotein 12), PSG6, CGM3 PSG10 PSG12 PSGGB |
| UniProt Protein Function: | PSG6: a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 19q13.2 |
| UniProt Protein Details: | |
| NCBI Summary: | This gene is a member of the pregnancy-specific glycoprotein (PSG) gene family. The PSG genes are a subgroup of the carcinoembryonic antigen (CEA) family of immunoglobulin-like genes, and are found in a gene cluster at 19q13.1-q13.2 telomeric to another cluster of CEA-related genes. The PSG genes are expressed by placental trophoblasts and released into the maternal circulation during pregnancy, and are thought to be essential for maintenance of normal pregnancy. The protein encoded by this gene contains the Arg-Gly-Asp tripeptide associated with cellular adhesion and recognition. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012] |
| UniProt Code: | Q00889 |
| NCBI GenInfo Identifier: | 1709853 |
| NCBI Gene ID: | 5675 |
| NCBI Accession: | Q00889.1 |
| UniProt Secondary Accession: | Q00889,O75244, Q15224, Q15235, Q549K1 |
| UniProt Related Accession: | Q00889 |
| Molecular Weight: | 47,501 Da |
| NCBI Full Name: | Pregnancy-specific beta-1-glycoprotein 6 |
| NCBI Synonym Full Names: | pregnancy specific beta-1-glycoprotein 6 |
| NCBI Official Symbol: | PSG6Â Â |
| NCBI Official Synonym Symbols: | PSG10; PSGGB; PSBG-6; PSBG-10; PSBG-12Â Â |
| NCBI Protein Information: | pregnancy-specific beta-1-glycoprotein 6 |
| UniProt Protein Name: | Pregnancy-specific beta-1-glycoprotein 6 |
| UniProt Synonym Protein Names: | Pregnancy-specific beta-1-glycoprotein 10; PS-beta-G-10; PSBG-10; Pregnancy-specific glycoprotein 10; Pregnancy-specific beta-1-glycoprotein 12; PS-beta-G-12; PSBG-12; Pregnancy-specific glycoprotein 12 |
| Protein Family: | Pregnancy-specific beta-1-glycoprotein |
| UniProt Gene Name: | PSG6Â Â |
| UniProt Entry Name: | PSG6_HUMAN |
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