The PSG4 Polyclonal Antibody (PAC011521) is a valuable tool for researchers studying PSG4, a cell surface protein associated with pregnancy-specific glycoproteins. This antibody, generated in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot assays. By binding specifically to the PSG4 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an essential reagent for investigations in reproductive biology and pregnancy-related research.PSG4, a member of the pregnancy-specific glycoprotein family, plays a crucial role in regulating maternal-fetal interactions during pregnancy.
Its involvement in various reproductive processes underscores its potential significance in fertility, pregnancy complications, and maternal immune tolerance. Research on PSG4 may provide insights into the mechanisms governing normal and pathological pregnancies, opening up possibilities for novel therapeutic interventions targeting pregnancy-related disorders. Understanding the function of PSG4 is essential for advancing our knowledge of reproductive health and potentially improving maternal and fetal outcomes.
pregnancy specific beta-1-glycoprotein 4;PSG4;PSG9 ;CGM4, PSG9
UniProt Protein Function:
PSG4: Belongs to the immunoglobulin superfamily. CEA family. 2 isoforms of the human protein are produced by alternative splicingProtein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 19q13.2Biological Process: female pregnancy
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a pregnancy-specific glycoprotein (PSG), one of several encoded by a cluster of similar genes on chromosome 19. This gene is a member of the carcinoembryonic antigen (CEA) gene family and may play a role in regulation of the innate immune system. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]
