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PSG3 Antibody (PACO04784)

SKU:
PACO04784
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
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Description

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PSG3 Antibody (PACO04784)

The PSG3 Polyclonal Antibody (PACO04784) is a key tool for researchers studying PSG3, a protein associated with immune regulation and inflammation. The antibody, developed using rabbit immunization, exhibits high reactivity towards human samples and is validated for Western blot applications. By specifically binding to PSG3, this antibody allows for the precise detection and analysis of PSG3 in various cell types. This makes it an invaluable tool for investigations in immunology and cancer research.PSG3, also known as pregnancy-specific glycoprotein 3, is a protein with immunomodulatory properties that play a crucial role in immune response regulation.

It is involved in processes such as inflammation modulation and allergic response inhibition, making it a potential target for research into diseases like cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of PSG3 is essential for developing therapeutic strategies that manipulate immune responses in these disease contexts.

Antibody Name:PSG3 Antibody
Antibody SKU:PACO04784
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:IHC:1:100-1:300
Species Reactivity:Human
Immunogen:synthesized peptide derived from the Internal region of human PSG3.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:PSG3; Pregnancy-specific beta-1-glycoprotein 3; PS-beta-G-3; PSBG-3; Pregnancy-specific glycoprotein 3; Carcinoembryonic antigen SG5
UniProt Protein Function:PSG3: Belongs to the immunoglobulin superfamily. CEA family
UniProt Protein Details:

Protein type:Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular region

Biological Process: defense response; female pregnancy

NCBI Summary:The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
UniProt Code:Q16557
NCBI GenInfo Identifier:108935880
NCBI Gene ID:5671
NCBI Accession:Q16557.2
UniProt Related Accession:Q16557
Molecular Weight:47,945 Da
NCBI Full Name:Pregnancy-specific beta-1-glycoprotein 3
NCBI Synonym Full Names:pregnancy specific beta-1-glycoprotein 3
NCBI Official Symbol:PSG3  
NCBI Protein Information:pregnancy-specific beta-1-glycoprotein 3; PSBG-3; PS-beta-G-3; carcinoembryonic antigen SG5; pregnancy-specific glycoprotein 3
UniProt Protein Name:Pregnancy-specific beta-1-glycoprotein 3
UniProt Synonym Protein Names:Carcinoembryonic antigen SG5
Protein Family:Pregnancy-specific beta-1-glycoprotein
UniProt Gene Name:PSG3  

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