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PSG11 Antibody (PACO11520)

SKU:
PACO11520
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
$551
Frequently bought together:

Description

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PSG11 Antibody (PACO11520)

The PSG11 Polyclonal Antibody (PAC011520) is a valuable tool for researchers studying PSG11, a member of the pregnancy-specific glycoprotein family that plays a key role in pregnancy and immune regulation. Raised in rabbits, this antibody is highly specific to human samples and is validated for use in various applications, including Western blotting. By binding to the PSG11 protein, this antibody allows for accurate detection and analysis in different cell types, making it ideal for studies in reproductive biology and immunology.

PSG11 is known for its involvement in regulating immune responses during pregnancy, where it acts as an immunomodulatory factor to promote maternal-fetal tolerance. Its unique functions make it a potential target for research into complications such as pregnancy loss, preeclampsia, and fetal growth restriction. Understanding the mechanisms behind PSG11's immune regulatory role is crucial for developing interventions to support healthy pregnancy outcomes and prevent adverse complications.

Antibody Name:PSG11 Antibody (PACO11520)
Antibody SKU:PACO11520
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:
Species Reactivity:Human
Immunogen:Human PSG11
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:pregnancy specific beta-1-glycoprotein 11;PSG11;MGC22484;PSG13;PSG14 ;
UniProt Protein Function:PSG11: Belongs to the immunoglobulin superfamily. CEA family. 2 isoforms of the human protein are produced by alternative splicing
UniProt Protein Details:

Protein type:Secreted; Motility/polarity/chemotaxis; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 19q13.2

Cellular Component: extracellular region

Biological Process: female pregnancy

NCBI Summary:The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy. PSGs comprise a subgroup of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily. For additional general information about the PSG gene family, see PSG1 (MIM 176390).[supplied by OMIM, Oct 2009]
UniProt Code:Q9UQ72
NCBI GenInfo Identifier:164663826
NCBI Gene ID:5680
NCBI Accession:NP_001106881.1
UniProt Secondary Accession:Q9UQ72,Q13179, Q15242, Q8WW91, Q9UNE4,
UniProt Related Accession:Q9UQ72
Molecular Weight:37,146 Da
NCBI Full Name:pregnancy-specific beta-1-glycoprotein 11 isoform 2
NCBI Synonym Full Names:pregnancy specific beta-1-glycoprotein 11
NCBI Official Symbol:PSG11  
NCBI Official Synonym Symbols:PSG13; PSG14; PSBG-11; PSBG-13  
NCBI Protein Information:pregnancy-specific beta-1-glycoprotein 11; PS-beta-G-11; PS-beta-G-13; pregnancy-specific beta-1-glycoprotein 13
UniProt Protein Name:Pregnancy-specific beta-1-glycoprotein 11
UniProt Synonym Protein Names:Pregnancy-specific beta-1-glycoprotein 13; PS-beta-G-13; PSBG-13; Pregnancy-specific glycoprotein 13
Protein Family:Pregnancy-specific beta-1-glycoprotein
UniProt Gene Name:PSG11  
UniProt Entry Name:PSG11_HUMAN

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