The PSG1 Polyclonal Antibody (CAB6399) is a valuable tool for researchers studying PSG1, a member of the Pregnancy-Specific Glycoprotein family that is involved in immune regulation during pregnancy. This antibody, raised in rabbits, exhibits high reactivity with human samples and is recommended for use in Western blot applications. By binding specifically to the PSG1 protein, this antibody enables researchers to detect and analyze PSG1 in a variety of cell types, making it an ideal choice for studies related to reproductive biology and immune function.
PSG1 is known to play a critical role in promoting maternal-fetal tolerance, regulating immune responses in the placenta, and supporting normal pregnancy outcomes. Research on PSG1 is particularly relevant in understanding conditions such as preeclampsia, recurrent miscarriages, and other pregnancy-related disorders. By investigating the functions of PSG1, researchers can gain insights into mechanisms of immune tolerance and potentially develop novel therapeutic strategies for pregnancy complications.
Product Name:
PSG1 Rabbit Polyclonal Antibody
SKU:
CAB6399
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 180-419 of human PSG1 (NP_001171754.1).
The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).
Purification Method:
Affinity purification
Gene ID:
5669
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using PSG1 Rabbit pAb (CAB6399) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
