The PSD Antibody (PAC054042) is a polyclonal antibody designed for research involving PSD, a key protein involved in synaptic plasticity and neurological function. This antibody, raised in rabbits, is highly reactive with human samples and is validated for use in applications such as Western blot and immunohistochemistry.PSD, also known as postsynaptic density protein, plays a crucial role in the organization and regulation of synaptic neurotransmission. It is involved in signal transduction pathways and synaptic strength, making it an essential target for studies in neuroscience and neurodegenerative diseases. Understanding the function and regulation of PSD is essential for uncovering the mechanisms underlying cognitive function and neurological disorders.
This antibody specifically binds to the PSD protein, enabling researchers to detect and analyze its expression in various cell types and tissues. Its high specificity and sensitivity make it an ideal tool for investigating the role of PSD in synaptic plasticity, learning and memory, and neurodevelopmental disorders. By studying PSD, researchers can gain valuable insights into the mechanisms underlying brain function and potential therapeutic targets for neurological conditions.
PH and SEC7 domain-containing protein 1 (Exchange factor for ADP-ribosylation factor guanine nucleotide factor 6) (Exchange factor for ARF6) (Exchange factor for ARF6 A) (Pleckstrin homology and SEC7 domain-containing protein 1), PSD, EFA6 EFA6A KIAA2011 PSD1 TYL
UniProt Protein Function:
PSD: Guanine nucleotide exchange factor for ARF6. Induces cytoskeletal remodeling. Belongs to the PSD family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: GEFs; GEFs, ARFChromosomal Location of Human Ortholog: 10q24Cellular Component: ruffle; integral to membrane; plasma membrane; trans-Golgi network; cell junctionMolecular Function: signal transducer activity; protein binding; phospholipid binding; ARF guanyl-nucleotide exchange factor activityBiological Process: vesicle-mediated transport; neuron differentiation; regulation of ARF protein signal transduction; signal transduction; positive regulation of GTPase activity
UniProt Protein Details:
NCBI Summary:
This gene encodes a Plekstrin homology and SEC7 domains-containing protein that functions as a guanine nucleotide exchange factor. The encoded protein regulates signal transduction by activating ADP-ribosylation factor 6. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2012]
