The PRX Polyclonal Antibody (CAB17744) is a valuable tool for researchers studying the PRX protein, which plays a critical role in oxidative stress regulation and cell protection. This antibody, raised in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By targeting the PRX protein, this antibody enables the detection and analysis of PRX in various cell types, making it an essential component for studies in oxidative stress, cell biology, and disease research.PRX, also known as peroxiredoxin, is a key antioxidant enzyme that helps protect cells from oxidative damage and maintains cellular redox balance.
Dysregulation of PRX has been associated with a variety of diseases, including cancer, neurodegenerative disorders, and cardiovascular conditions. Understanding the role of PRX in oxidative stress and cell signaling pathways is crucial for developing targeted therapies and interventions for these diseases.Overall, the PRX Polyclonal Antibody (CAB17744) serves as a reliable tool for researchers seeking to explore the function and mechanisms of PRX in health and disease. Its specificity and sensitivity make it an ideal choice for studies aiming to uncover the therapeutic potential of targeting PRX in various pathological conditions.
Product Name:
PRX Rabbit Polyclonal Antibody
SKU:
CAB17744
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1250-1350 of human PRX (NP_870998.2).
This gene encodes a protein involved in peripheral nerve myelin upkeep. The encoded protein contains 2 PDZ domains which were named after PSD95 (post synaptic density protein), DlgA (Drosophila disc large tumor suppressor), and ZO1 (a mammalian tight junction protein). Two alternatively spliced transcript variants have been described for this gene which encode different protein isoforms and which are targeted differently in the Schwann cell. Mutations in this gene cause Charcot-Marie-Tooth neuoropathy, type 4F and Dejerine-Sottas neuropathy.
Purification Method:
Affinity purification
Gene ID:
57716
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRX Rabbit pAb (CAB17744) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
