PRUNE Antibody (PACO11512)
- SKU:
- PACO11512
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- IF
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Frequently bought together:
Description
Antibody Name: | PRUNE Antibody (PACO11512) |
Antibody SKU: | PACO11512 |
Size: | 50ul |
Host Species: | Rabbit |
Tested Applications: | ELISA, WB, IHC, IF |
Recommended Dilutions: | |
Species Reactivity: | Human, Mouse, Rat |
Immunogen: | Human PRUNE |
Form: | Liquid |
Storage Buffer: | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
Purification Method: | Antigen Affinity purified |
Clonality: | Polyclonal |
Isotype: | IgG |
Conjugate: | Non-conjugated |
Synonyms: | prune homolog (Drosophila);PRUNE;DRES-17;HTCD37 ; |
UniProt Protein Function: | PRUNE: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. Belongs to the PPase class C family. Prune subfamily. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; EC 3.6.1.1; Nucleotide Metabolism - purineChromosomal Location of Human Ortholog: 1q21Cellular Component: cytoplasmMolecular Function: protein binding |
UniProt Protein Details: | |
NCBI Summary: | This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014] |
UniProt Code: | Q86TP1 |
NCBI GenInfo Identifier: | 229462737 |
NCBI Gene ID: | 58497 |
NCBI Accession: | Q86TP1.2 |
UniProt Secondary Accession: | Q86TP1,Q5SZF9, Q659E5, Q6P4E0, Q8N654, Q96JU5, Q9C071 Q9C072, Q9UIV0, B2RCH8 |
UniProt Related Accession: | Q86TP1 |
Molecular Weight: | 24,475 Da |
NCBI Full Name: | Protein prune homolog |
NCBI Synonym Full Names: | prune exopolyphosphatase |
NCBI Official Symbol: | PRUNE1Â Â |
NCBI Official Synonym Symbols: | PRUNE; DRES17; HTCD37; DRES-17; H-PRUNEÂ Â |
NCBI Protein Information: | protein prune homolog |
UniProt Protein Name: | Protein prune homolog |
UniProt Synonym Protein Names: | Drosophila-related expressed sequence 17; DRES-17; DRES17; HTcD37 |
Protein Family: | Protein prune |
UniProt Gene Name: | PRUNEÂ Â |
UniProt Entry Name: | PRUNE_HUMAN |