The Prune Antibody (PACO11512) is a high-quality polyclonal antibody specifically designed for the detection and analysis of Prune, a protein involved in various cellular processes such as cell migration and adhesion. This antibody is produced by Assay Genie using advanced techniques, ensuring high reactivity with human samples and reliable results in experiments.The Prune Antibody binds specifically to the Prune protein, allowing for accurate detection and quantification in a variety of cell types. It is validated for use in Western blot applications, making it a valuable tool for researchers studying cell biology, cancer, and other related fields.
Prune is known for its role in promoting cell migration and invasion, making it a potential target for cancer research and therapy development. By understanding the function of Prune and its interactions with other proteins, researchers can gain insights into the mechanisms underlying cancer progression and potentially uncover new therapeutic strategies.Overall, the Prune Antibody (PACO11512) is a reliable and effective tool for research involving the Prune protein, offering valuable insights into its role in cellular processes and its potential implications in cancer biology.
PRUNE: Phosphodiesterase (PDE) that has higher activity toward cAMP than cGMP, as substrate. Plays a role in cell proliferation, is able to induce cell motility and acts as a negative regulator of NME1. Belongs to the PPase class C family. Prune subfamily. 7 isoforms of the human protein are produced by alternative splicing.Protein type: Hydrolase; EC 3.6.1.1; Nucleotide Metabolism - purineChromosomal Location of Human Ortholog: 1q21Cellular Component: cytoplasmMolecular Function: protein binding
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the DHH protein superfamily of phosphoesterases. This protein has been found to function as both a nucleotide phosphodiesterase and an exopolyphosphatase. This protein is believed to stimulate cancer progression and metastases through the induction of cell motility. A pseuodgene has been identified on chromosome 13. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2014]
