The PRTN3 Polyclonal Antibody (CAB17522) is a valuable tool for researchers studying the PRTN3 protein, a key player in immune regulation and inflammation. Raised in rabbits, this antibody exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the PRTN3 protein, it enables accurate detection and analysis in a variety of cell types, making it an ideal choice for studies in immunology and inflammatory conditions.
PRTN3, also known as myeloblastin, is a serine protease involved in the regulation of immune responses and inflammatory processes. Its dysregulation has been implicated in autoimmune diseases, vasculitis, and other inflammatory conditions, making it a promising target for therapeutic interventions. Research on PRTN3 can provide valuable insights into the mechanisms underlying these diseases and aid in the development of novel treatment strategies.
Product Name:
PRTN3 Rabbit Polyclonal Antibody
SKU:
CAB17522
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 28-170 of human Proteinase 3/PR3 (NP_002768.3).
Enables enzyme binding activity; serine-type endopeptidase activity; and signaling receptor binding activity. Involved in several processes, including mature conventional dendritic cell differentiation; membrane protein ectodomain proteolysis; and neutrophil extravasation. Located in azurophil granule lumen; cytosol; and plasma membrane raft. Colocalizes with plasma membrane.
Purification Method:
Affinity purification
Gene ID:
5657
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat lung, using Proteinase 3/PR3 Rabbit pAb (CAB17522) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
