The PRTFDC1 Polyclonal Antibody (PAC04234) is a valuable tool for researchers studying the PRTFDC1 protein, known for its role in various cellular processes. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in a variety of applications, including Western blotting. By targeting the PRTFDC1 protein, this antibody allows for the detection and analysis of PRTFDC1 expression in different cell types, making it an essential tool for studies in cell biology and molecular biology.
PRTFDC1, a protein involved in cell proliferation and differentiation, is essential for maintaining cellular homeostasis. Its functions are implicated in various diseases, including cancer and developmental disorders, making it a target of interest for researchers investigating these conditions. By understanding the role of PRTFDC1 in cellular processes, researchers can gain insights that may lead to the development of novel therapeutics targeting PRTFDC1-related pathways.
Antibody Name:
PRTFDC1 Antibody (PACO42234)
Antibody SKU:
PACO42234
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:20-1:200
Species Reactivity:
Human
Immunogen:
Recombinant Human Phosphoribosyltransferase domain-containing protein 1 (2-225AA)
Immunohistochemistry of paraffin-embedded human testis tissue using PACO42234 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human ovarian cancer using PACO42234 at dilution of 1:100.
Background:
Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage.
Synonyms:
Phosphoribosyltransferase domain-containing protein 1, PRTFDC1, HHGP
UniProt Protein Function:
PRTFDC1: Has low, barely detectable phosphoribosyltransferase activity (in vitro). Binds GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). Is not expected to contribute to purine metabolism or GMP salvage. Belongs to the purine/pyrimidine phosphoribosyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Chromosomal Location of Human Ortholog: 10p12.1
Cellular Component: cytosol
Molecular Function:hypoxanthine phosphoribosyltransferase activity; magnesium ion binding; protein binding; protein homodimerization activity
