PRSS8 Rabbit Polyclonal Antibody (CAB16419)
- SKU:
- CAB16419
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PRSS8 Rabbit Polyclonal Antibody |
SKU: | CAB16419 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200 to the C-terminus of human PRSS8 (NP_002764.1). |
Sequence: | TCNC LYNI DAKP EEPH FVQE DMVC AGYV EGGK DACQ GDSG GPLS CPVE GLWY LTGI VSWG DACG ARNR PGVY TLAS SYAS WIQS KVTE LQPR VVPQ TQES QPDS NLCG SHLA FSSA PAQG LLRP ILFL PLGL ALGL LSPW LSEH |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CAP1; PROSTASIN; PRSS8 |
Positive Sample: | Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Secreted, Single-pass membrane protein, extracellular space, extracellular space. |
Calculated MW: | 36kDa |
Observed MW: | 36kDa |
This gene encodes a member of the peptidase S1 or chymotrypsin family of serine proteases. The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate via a disulfide bond to form the heterodimeric enzyme. This enzyme is highly expressed in prostate epithelia and is one of several proteolytic enzymes found in seminal fluid. This protease exhibits trypsin-like substrate specificity, cleaving protein substrates at the carboxyl terminus of lysine or arginine residues. The encoded protease partially mediates proteolytic activation of the epithelial sodium channel, a regulator of sodium balance, and may also play a role in epithelial barrier formation.
Purification Method: | Affinity purification |
Gene ID: | 5652 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |