The PRSS56 Polyclonal Antibody (PAC050266) is a valuable tool for studying PRSS56, a protein involved in eye development and potentially linked to myopia. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in various research applications, including Western blot and immunohistochemistry.PRSS56, also known as serine protease 56, is believed to play a crucial role in the regulation of eye growth and refractive errors. Research has suggested that mutations in the PRSS56 gene may contribute to the development of myopia, a common vision disorder characterized by elongation of the eye axis.
By studying PRSS56 using this antibody, researchers can gain insights into the mechanisms underlying myopia and potentially identify novel therapeutic targets for its treatment.Overall, the PRSS56 Polyclonal Antibody (PAC050266) is a valuable tool for researchers interested in exploring the role of PRSS56 in eye development and myopia. Its high specificity and reactivity with human samples make it a reliable choice for studies in ophthalmology, genetics, and vision science.
Western Blot. Positive WB detected in: Rat liver tissue, Rat spleen tissue. All lanes: PRSS56 antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 65 kDa. Observed band size: 65 kDa..
Immunohistochemistry of paraffin-embedded human eye tissue using PACO50266 at dilution of 1:100.
Background:
Serine protease required during eye development.
Synonyms:
Serine protease 56 (EC 3.4.21), PRSS56
UniProt Protein Function:
PRSS56: Serine protease required during eye development. Belongs to the peptidase S1 familyChromosomal Location of Human Ortholog: 2q37.1Cellular Component: endoplasmic reticulumMolecular Function: serine-type endopeptidase activityBiological Process: camera-type eye development; proteolysisDisease: Microphthalmia, Isolated 6
UniProt Protein Details:
NCBI Summary:
This gene encodes a protein that contains a peptidase S1 domain and possesses trypsin-like serine protease activity. The encoded protein may play a role in eye development, and mutations in this gene are a cause of autosomal recessive posterior microphthalmos. [provided by RefSeq, Dec 2011]
