null

PRSS3 Antibody (PACO33212)

SKU:
PACO33212
Product Type:
Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
  • PRSS3 Antibody PACO33212
  • PRSS3 Antibody PACO33212
€339

Description

system_update_altDatasheetsystem_update_altMSDS

PRSS3 Antibody (PACO33212)

The PRSS3 Polyclonal Antibody (PAC033212) is a valuable tool for researchers studying the PRSS3 protein, a serine protease involved in various physiological processes, including digestion and immune regulation. This antibody, produced in rabbits, has high reactivity with human samples and has been validated for use in Western blot applications, enabling researchers to detect and analyze PRSS3 in different cell types.PRSS3, also known as Mesotrypsin, is an enzyme that plays a crucial role in protein degradation and has been implicated in various diseases, including cancer and inflammatory conditions.

By targeting PRSS3, researchers can gain insight into its function and potential therapeutic applications in these disease contexts. Understanding the role of PRSS3 is essential for developing targeted interventions to modulate its activity and potentially treat related medical conditions.

Antibody Name:PRSS3 Antibody (PACO33212)
Antibody SKU:PACO33212
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, WB, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, WB:1:1000-1:5000, IHC:1:20-1:200
Species Reactivity:Human
Immunogen:Recombinant Human Trypsin-3 protein (81-303AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageWestern Blot
Positive WB detected in: U87 whole cell lysate
All lanes: PRSS3 antibody at 3µg/ml
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 33, 29, 27, 26 kDa
Observed band size: 27 kDa
.
Product ImageIHC image of PACO33212 diluted at 1:100 and staining in paraffin-embedded human pancreatic tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:Digestive protease specialized for the degradation of trypsin inhibitors.
Synonyms:Trypsin-3 (EC 3.4.21.4) (Brain trypsinogen) (Mesotrypsinogen) (Serine protease 3) (Serine protease 4) (Trypsin III) (Trypsin IV), PRSS3, PRSS4 TRY3 TRY4
UniProt Protein Function:Digestive protease specialized for the degradation of trypsin inhibitors. In the ileum, may be involved in defensin processing, including DEFA5.
UniProt Protein Details:
NCBI Summary:This gene encodes a trypsinogen, which is a member of the trypsin family of serine proteases. This enzyme is expressed in the brain and pancreas and is resistant to common trypsin inhibitors. It is active on peptide linkages involving the carboxyl group of lysine or arginine. This gene is localized to the locus of T cell receptor beta variable orphans on chromosome 9. Four transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2010]
UniProt Code:P35030
NCBI GenInfo Identifier:209572698
NCBI Gene ID:5646
NCBI Accession:P35030.2
UniProt Secondary Accession:P35030,P15951, Q15665, Q5VXV0, Q6ISJ4, Q9UQV3, A8CED1 A8CED3, A9Z1Y4, E7ES07
UniProt Related Accession:P35030
Molecular Weight:25,924 Da
NCBI Full Name:Trypsin-3
NCBI Synonym Full Names:protease, serine 3
NCBI Official Symbol:PRSS3  
NCBI Official Synonym Symbols:T9; MTG; TRY3; TRY4; PRSS4  
NCBI Protein Information:trypsin-3
UniProt Protein Name:Trypsin-3
UniProt Synonym Protein Names:Brain trypsinogen; Mesotrypsinogen; Serine protease 3; Serine protease 4; Trypsin III; Trypsin IV
Protein Family:
UniProt Gene Name:PRSS3  
UniProt Entry Name:TRY3_HUMAN
Antibodies
PRSS3 Antibody (PACO01660)
Secondary Antibody
Anti-HRP Goat Anti-Rabbit IgG (H+L) Antibody (CABS014)
Recommended Products
Anti-FITC Goat Anti-Rabbit IgG (H+L) Antibody (CABS011)
Anti-HRP-conjugated Beta Actin Antibody (CABC028)

Related Products