PRSS12 Rabbit Polyclonal Antibody (CAB14319)
- SKU:
- CAB14319
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | PRSS12 Rabbit Polyclonal Antibody |
SKU: | CAB14319 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 21-300 of human PRSS12 (NP_003610.2). |
Sequence: | FDSV LNDS LHHS HRHS PPAG PHYP YYLP TQQR PPRT RPPP PLPR FPRP PRAL PAQR PHAL QAGH TPRP HPWG CPAG EPWV SVTD FGAP CLRW AEVP PFLE RSPP ASWA QLRG QRHN FCRS PDGA GRPW CFYG DARG KVDW GYCD CRHG SVRL RGGK NEFE GTVE VYAS GVWG TVCS SHWD DSDA SVIC HQLQ LGGK GIAK QTPF SGLG LIPI YWSN VRCR GDEE NILL CEKD IWQG GVCP QKMA AAVT CSFS HGPT FPII RLAG GSSV HEGR VELY HAGQ |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | MRT1; BSSP3; BSSP-3; PRSS12 |
Positive Sample: | Mouse testis,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 97kDa |
Observed MW: | 97kDa |
This gene encodes a member of the trypsin family of serine proteases and contains a signal peptide, a proline-rich region, a Kringle domain, four scavenger receptor cysteine-rich domains, and a trypsin-like serine protease domain. The protein, sometimes referred to as neurotrypsin or motopsin, is secreted from neuronal cells and localizes to the synaptic cleft. Studies in mice show that this protein cleaves a protein, agrin, that is important for the formation and maintenance of exitatory synapses. Defects in this gene cause a form of autosomal recessive cognitive impairment (MRT1).
Purification Method: | Affinity purification |
Gene ID: | 8492 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |