The PRRX1 Polyclonal Antibody (CAB10237) is a valuable tool for researchers studying the PRRX1 protein, which plays a key role in embryonic development and has been implicated in cancer progression. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the PRRX1 protein, this antibody allows for the detection and analysis of PRRX1 expression in a variety of cell types, making it ideal for studies in developmental biology and cancer research.
PRRX1 is a transcription factor that regulates mesenchymal cell differentiation and is known to be dysregulated in various cancer types, including breast, prostate, and lung cancer. Understanding the role of PRRX1 in these processes is crucial for identifying novel therapeutic targets and developing effective treatments for cancer. With its high specificity and sensitivity, the PRRX1 Polyclonal Antibody is a valuable tool for researchers working in this field.
Product Name:
PRRX1 Rabbit Polyclonal Antibody
SKU:
CAB10237
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-90 of human PRRX1 (NP_073207.1).
The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns.
Purification Method:
Affinity purification
Gene ID:
5396
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of HeLa, using PRRX1 antibody (CAB10237) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
