The PRRG2 Polyclonal Antibody (CAB14380) is an essential tool for researchers studying the PRRG2 protein, which is known for its involvement in immune response modulation and inflammation regulation. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.PRRG2, also referred to as immune regulatory receptor, plays a pivotal role in maintaining immune homeostasis by modulating inflammatory responses and allergic reactions. Its influence on immune function highlights its significance in understanding diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
By targeting the PRRG2 protein, researchers can gain insights into the mechanisms underlying immune regulation and potentially develop novel therapies for diseases characterized by dysregulated immune responses. The PRRG2 Polyclonal Antibody serves as a valuable tool for detecting and analyzing PRRG2 expression in various cell types, making it an ideal choice for immunology and cancer research studies.
Product Name:
PRRG2 Rabbit Polyclonal Antibody
SKU:
CAB14380
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-179 of human PRRG2 (NP_001303264.1).
The protein encoded by this gene is a single-pass transmembrane protein containing an N-terminal gamma-carboxyglutamic acid (Gla) domain and tandem Pro/Leu-Pro-Xaa-Tyr (PY) motifs at its C-terminal end. The Gla domain is exposed on the cell surface while the PY motifs are cytoplasmic. The PY motifs of the encoded protein have been shown to interact with YAP1, a WW domain-containing protein. Therefore, it is thought that the encoded protein may be part of a signal transduction pathway. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
5639
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRRG2 Rabbit pAb (CAB14380) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 15s.
