The PRPSAP2 Polyclonal Antibody (CAB15711) is specifically designed for research involving PRPSAP2, a protein known to play a role in nucleotide biosynthesis and metabolism. This antibody, raised in rabbits, is highly reactive with human samples and has been validated for use in Western blot applications. By binding to the PRPSAP2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal tool for studies in molecular biology and biochemistry.PRPSAP2 is a crucial enzyme involved in the synthesis of purine nucleotides, which are essential for DNA and RNA production.
Dysregulation of PRPSAP2 has been linked to various diseases, including cancer and metabolic disorders. By studying the function of PRPSAP2, researchers can gain insights into these diseases and potentially identify new therapeutic targets.Overall, the PRPSAP2 Polyclonal Antibody is a valuable tool for researchers interested in the molecular mechanisms underlying nucleotide metabolism and its implications for human health. Its high reactivity and specificity make it a reliable choice for studies in biochemistry, genetics, and drug development.
Product Name:
PRPSAP2 Rabbit Polyclonal Antibody
SKU:
CAB15711
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 211-252 of human PRPSAP2 (NP_001340030.1).
This gene encodes a protein that associates with the enzyme phosphoribosylpyrophosphate synthetase (PRS). PRS catalyzes the formation of phosphoribosylpyrophosphate which is a substrate for synthesis of purine and pyrimidine nucleotides, histidine, tryptophan and NAD. PRS exists as a complex with two catalytic subunits and two associated subunits. This gene encodes a non-catalytic associated subunit of PRS. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5636
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRPSAP2 Rabbit pAb (CAB15711) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
