The PRPS2 Polyclonal Antibody (CAB12645) is a valuable tool for researchers studying the PRPS2 protein, which is involved in nucleotide biosynthesis and cell metabolism. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the PRPS2 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in molecular biology and cancer research.PRPS2 is a key enzyme in the purine biosynthesis pathway, playing a crucial role in maintaining cellular energy levels and nucleotide pool balance.
Dysregulation of PRPS2 has been associated with various diseases, including cancer and metabolic disorders. Therefore, studying the function of PRPS2 is essential for gaining insights into these conditions and developing targeted therapies.Overall, the PRPS2 Polyclonal Antibody (CAB12645) offers researchers a reliable tool for investigating the role of PRPS2 in cellular metabolism, cancer biology, and related fields, ultimately contributing to advancements in medicine and drug development.
Product Name:
PRPS2 Rabbit Polyclonal Antibody
SKU:
CAB12645
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PRPS2 (NP_002756.1).
This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRPS2 Rabbit pAb (CAB12645) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
