The PRPS2 Polyclonal Antibody (CAB12644) is a valuable tool for researchers studying PRPS2, a key enzyme involved in nucleotide biosynthesis and cellular metabolism. This antibody, generated in rabbits, is highly specific for human PRPS2 and has been validated for use in Western blotting applications.PRPS2 plays a crucial role in maintaining nucleotide pools for DNA and RNA synthesis, making it essential for cell proliferation and growth. Dysregulation of PRPS2 has been implicated in various diseases, including cancer and metabolic disorders.
By detecting and analyzing PRPS2 levels in different cell types, researchers can gain valuable insights into the role of this enzyme in disease pathogenesis.The PRPS2 Polyclonal Antibody (CAB12644) provides a reliable tool for studying PRPS2 expression in various biological samples, making it ideal for research in molecular biology, oncology, and metabolic diseases. By understanding the functions of PRPS2, researchers can develop targeted therapies aimed at modulating nucleotide metabolism and cell growth in disease settings.
Product Name:
PRPS2 Rabbit Polyclonal Antibody
SKU:
CAB12644
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human PRPS2 (NP_002756.1).
This gene encodes a phosphoribosyl pyrophosphate synthetase that plays a central role in the synthesis of purines and pyrimidines. The encoded protein catalyzes the synthesis of 5-phosphoribosyl 1-pyrophosphate from ATP and D-ribose 5-phosphate. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
5634
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRPS2 Rabbit pAb (CAB12644) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
