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PRPS1 Monoclonal Antibody [PAT1E11AT] (CPAB0184)

SKU:
CPAB0184
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT1E11AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

PRPS1 Monoclonal Antibody [PAT1E11AT] (CPAB0184)

Similarly, the PRPS1 Polyclonal Antibody (CPAB0184) is a valuable tool for research related to PRPS1, an enzyme involved in nucleotide biosynthesis and purine metabolism. This antibody, produced in rabbits, exhibits high specificity for human samples and is suitable for Western blotting applications. By binding to the PRPS1 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it suitable for investigations in biochemistry and molecular biology.PRPS1, also known as phosphoribosyl pyrophosphate synthetase 1, is essential for the synthesis of purine nucleotides, which are crucial for DNA and RNA production.

Dysregulation of PRPS1 has been linked to a variety of genetic disorders and cancer types, highlighting its importance in cellular function. Research on PRPS1 can provide insights into nucleotide metabolism, cell proliferation, and disease mechanisms, offering potential targets for therapeutic interventions in various pathological conditions.

Product Name:PRPS1 Antibody
Product Sku:CPAB0184
Size:5μg
Host Species:Mouse
Immunogen:Anti-human PRPS1 mAb, clone PAT1E11AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PRPS1 protein 1-318 amino acids purified from Ecoli.
Clone:PAT1E11AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:PRPS1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:PRPS1 catalyzes the synthesis of phosphoribosylpyrophosphate (PRPP) that is essential for nucleotide synthesis. PRPS1 catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is essential for purine metabolism and nucleotide biosynthesis. Defects in PRPS1 result in phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome.
Synonyms:ARTS, CMTX5, PPRibP, PRSI, DFN2, Ribose-phosphate pyrophosphokinase 1, DFNX1, Phosphoribosyl pyrophosphate synthase I, PRS-I, PRPS1, KIAA0967.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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