PRPF8 Rabbit Monoclonal Antibody (CAB4575)
- SKU:
- CAB4575
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- HPRP8
- PRP8
- PRPC8
- RP13
- SNRNP220
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PRPF8 Rabbit Monoclonal Antibody |
SKU: | CAB4575 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 2200-2335 of human PRPF8 (Q6P2Q9). |
Sequence: | MADN PSWD GEKT IIIT CSFT PGSC TLTA YKLT PSGY EWGR QNTD KGNN PKGY LPSH YERV QMLL SDRF LGFF MVPA QSSW NYNF MGVR HDPN MKYE LQLA NPKE FYHE VHRP SHFL NFAL LQEG EVYS ADRE DLYA |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | PRP8; RP13; HPRP8; PRPC8; SNRNP220; PRPF8 |
Positive Sample: | HeLa,293T,Jurkat,Mouse brain,Mouse spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus speckle. |
Calculated MW: | 274kDa |
Observed MW: | 274kDa |
Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.
Purification Method: | Affinity purification |
Gene ID: | 10594 |
Clone Number: | ARC1038 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |