The PRPF40A Polyclonal Antibody (PAC011498) is a vital tool for researchers studying PRPF40A, a protein involved in mRNA splicing processes. This antibody, produced in-house and rigorously validated for use in various applications, is highly specific to human samples.PRPF40A is a key player in the spliceosome machinery, essential for removing introns and joining exons to generate mature mRNA. Dysregulation of this process can lead to various diseases, including cancer and genetic disorders. The PRPF40A Polyclonal Antibody enables the detection and analysis of PRPF40A protein levels in different cell types, providing valuable insights into its functions and potential implications in disease development.
By studying PRPF40A, researchers can unravel its role in mRNA splicing and its impact on gene expression regulation. This antibody serves as a reliable tool for investigating the molecular mechanisms underlying various physiological and pathological conditions, paving the way for the development of targeted therapies and diagnostic tools.
PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae);PRPF40A;FBP-11;FBP11;FLAF1;FLJ20585;FNBP3;HIP10;HYPA;NY-REN-6 ;
UniProt Protein Function:
FNBP3: Binds to WASL/N-WASP and suppresses its translocation from the nucleus to the cytoplasm, thereby inhibiting its cytoplasmic function. Plays a role in the regulation of cell morphology and cytoskeletal organization. Required in the control of cell shape and migration. May play a role in cytokinesis. May be involved in pre-mRNA splicing. Belongs to the PRPF40 family. 4 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processing; SpliceosomeChromosomal Location of Human Ortholog: 2q23.3Cellular Component: cytoplasm; membrane; nuclear matrix; nucleoplasm; snRNP U1Molecular Function: protein binding; RNA bindingBiological Process: cell migration; cytoskeleton organization and biogenesis; nuclear mRNA splicing, via spliceosome; regulation of cell shape; regulation of cytokinesis
