The PRPF39 Antibody (PAC022520) is a high-quality polyclonal antibody specifically targeted towards the PRPF39 protein, a spliceosome-associated factor essential for pre-mRNA splicing. This antibody, raised in rabbits, has been rigorously validated for use in various applications, including Western blot and immunohistochemistry.PRPF39 is a key player in the spliceosome machinery, facilitating the removal of introns from pre-mRNA to generate mature mRNA transcripts. Dysregulation of PRPF39 has been linked to various diseases, including cancer and genetic disorders, making it a promising target for research in the fields of molecular biology and genetics.
By using the PRPF39 Antibody, researchers can effectively detect and analyze PRPF39 expression in different cell types and tissues, providing valuable insights into its function and potential implications in disease pathology. This antibody is a valuable tool for investigating the role of PRPF39 in splicing regulation and its impact on cellular processes, offering new opportunities for therapeutic interventions and drug discovery efforts.
Antibody Name:
PRPF39 Antibody (PACO22520)
Antibody SKU:
PACO22520
Size:
100ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:500-1:3000
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from internal of human PRPF39.
Form:
Liquid
Storage Buffer:
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Western blot analysis of extracts from K562 cells, using PRPF39 antibody.
PRPF39: Involved in pre-mRNA splicing. Belongs to the PRP39 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processingChromosomal Location of Human Ortholog: 14q21.2Cellular Component: snRNP U1Molecular Function: pre-mRNA 5'-splice site bindingBiological Process: nuclear mRNA 5'-splice site recognition
