The PRPF39 Polyclonal Antibody (PACO4670) is a valuable tool for researchers investigating the PRPF39 protein, which is essential for pre-mRNA splicing and mRNA processing. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used with human samples, making it a reliable choice for Western blot applications. By targeting the PRPF39 protein, this antibody enables researchers to detect and analyze its expression in various cell types, offering insights into its role in gene regulation and RNA processing.PRPF39 is a critical component of the spliceosome complex, which is responsible for removing introns from pre-mRNA molecules.
Dysregulation of PRPF39 has been implicated in various diseases, including cancer and neurological disorders, highlighting its importance in cellular processes. By studying the function of PRPF39, researchers can gain a better understanding of mRNA splicing mechanisms and potentially identify novel therapeutic targets for disease intervention.Overall, the PRPF39 Polyclonal Antibody (PACO4670) is a valuable resource for researchers interested in unraveling the complex process of mRNA splicing and its implications for human health. Its versatility and reliability make it an essential tool for studies in molecular biology, genetics, and disease pathology.
Antibody Name:
PRPF39 Antibody
Antibody SKU:
PACO04670
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the Internal region of human PRPF39.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
PRPF39: Involved in pre-mRNA splicing. Belongs to the PRP39 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA processingChromosomal Location of Human Ortholog: 14q21.2Cellular Component: snRNP U1Molecular Function: pre-mRNA 5'-splice site bindingBiological Process: nuclear mRNA 5'-splice site recognition
