The PRPF38A Polyclonal Antibody (PACO05548) is a vital tool for researchers studying PRPF38A, a protein involved in mRNA splicing and RNA processing. Designed for use in immunohistochemistry and Western blot applications, this antibody specifically binds to PRPF38A in human samples, allowing for accurate detection and analysis in various cell types.PRPF38A, a key component of the spliceosome complex, plays a crucial role in ensuring the correct splicing of pre-mRNA molecules. Dysregulation of PRPF38A has been linked to various diseases, including neurological disorders and cancer.
By studying the function and regulation of PRPF38A, researchers can gain insights into the molecular mechanisms underlying these conditions, potentially leading to the development of targeted therapies.With its high reactivity and specificity, the PRPF38A Polyclonal Antibody is an essential tool for researchers looking to deepen their understanding of mRNA splicing processes and their implications for human health. Its versatility and reliability make it a valuable asset for studies in molecular biology, genetics, and disease pathology.
Antibody Name:
PRPF38A Antibody (PACO05548)
Antibody SKU:
PACO05548
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB, IHC
Recommended Dilutions:
ELISA:1:20000, WB:1:500-1:2000, IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
Synthesized peptide derived from the Internal region of human PRPF38A.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
PRPF38A; Pre-mRNA-splicing factor 38A
UniProt Protein Function:
PRPF38A: May be required for pre-mRNA splicing (Potential). Belongs to the PRP38 family. 2 isoforms of the human protein are produced by alternative splicing.Protein type: RNA splicingChromosomal Location of Human Ortholog: 1p32.3Cellular Component: nuclear membrane; nucleusMolecular Function: protein binding
