The PRPF31 Polyclonal Antibody (CAB5732) is a valuable tool for researchers studying PRPF31, a protein involved in pre-mRNA splicing and critical for cell function. This antibody is produced in rabbits, with high reactivity towards human samples, and is validated for use in Western blot applications. By targeting the PRPF31 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for research in molecular biology and genetics.
PRPF31 is essential for proper spliceosome assembly and function, making it a key player in gene expression regulation. Mutations in the PRPF31 gene are associated with diseases such as retinitis pigmentosa, highlighting the importance of understanding its role in cellular processes. By studying PRPF31 using this antibody, researchers can further uncover its function and potential implications in disease pathology.
Product Name:
PRPF31 Rabbit Polyclonal Antibody
SKU:
CAB5732
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human PRPF31 (NP_056444.3).
This gene encodes a component of the spliceosome complex and is one of several retinitis pigmentosa-causing genes. When the gene product is added to the spliceosome complex, activation occurs.
Purification Method:
Affinity purification
Gene ID:
26121
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using PRPF31 Rabbit pAb (CAB5732) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
