PRP19 Rabbit Polyclonal Antibody (CAB6706)
- SKU:
- CAB6706
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PRP19 Rabbit Polyclonal Antibody |
SKU: | CAB6706 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human PRP19 (NP_055317.1). |
Sequence: | MSLI CSIS NEVP EHPC VSPV SNHV YERR LIEK YIAE NGTD PINN QPLS EEQL IDIK VAHP IRPK PPSA TSIP AILK ALQD EWDA VMLH SFTL RQQL QTTR QELS HALY QHDA ACRV IARL TKEV TAAR EALA TLKP QAGL IVPQ AVPS SQPS VVGA GEPM DLGE LVGM TPEI IQKL QDKA TVLT TERK KRGK TVPE ELVK PEEL SKYR QVAS HVGL HSAS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PSO4; SNEV; PRP19; UBOX4; hPSO4; NMP200 |
Positive Sample: | SW620 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Lipid droplet, Nucleus, cytoskeleton, nucleoplasm, spindle. |
Calculated MW: | 55kDa |
Observed MW: | 60kDa |
Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling; cellular protein metabolic process; and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm; nuclear speck; and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.
Purification Method: | Affinity purification |
Gene ID: | 27339 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |