PRP19 Rabbit Polyclonal Antibody (CAB12590)
- SKU:
- CAB12590
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | PRP19 Rabbit Polyclonal Antibody |
SKU: | CAB12590 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 127-416 of human PRP19 (NP_055317.1). |
Sequence: | AREA LATL KPQA GLIV PQAV PSSQ PSVV GAGE PMDL GELV GMTP EIIQ KLQD KATV LTTE RKKR GKTV PEEL VKPE ELSK YRQV ASHV GLHS ASIP GILA LDLC PSDT NKIL TGGA DKNV VVFD KSSE QILA TLKG HTKK VTSV VFHP SQDL VFSA SPDA TIRI WSVP NASC VQVV RAHE SAVT GLSL HATG DYLL SSSD DQYW AFSD IQTG RVLT KVTD ETSG CSLT CAQF HPDG LIFG TGTM DSQI KIWD LKER TNVA NFPG HSGP ITSI AFSE NGYY LATA ADDS SV |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | PSO4; SNEV; PRP19; UBOX4; hPSO4; NMP200 |
Positive Sample: | HepG2,Jurkat,HeLa,Mouse heart,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Lipid droplet, Nucleus, cytoskeleton, nucleoplasm, spindle. |
Calculated MW: | 55kDa |
Observed MW: | 55kDa |
Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling; cellular protein metabolic process; and mRNA splicing, via spliceosome. Acts upstream of or within protein polyubiquitination. Located in cytoplasm; nuclear speck; and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. Colocalizes with DNA replication factor A complex.
Purification Method: | Affinity purification |
Gene ID: | 27339 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |