PROZ Rabbit Polyclonal Antibody (CAB16082)
- SKU:
- CAB16082
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | PROZ Rabbit Polyclonal Antibody |
SKU: | CAB16082 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 220-340 of human PROZ (NP_003882.1). |
Sequence: | SLLH RNIT VKTY FNRT SQDP LMIK ITHV HVHM RYDA DAGE NDLS LLEL EWPI QCPG AGLP VCTP EKDF AEHL LIPR TRGL LSGW ARNG TDLG NSLT TRPV TLVE GEEC GQVL NVTV TTRT Y |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | PZ; PROZ |
Positive Sample: | HepG2,293T,Mouse kidney,Rat liver,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted |
Calculated MW: | 45kDa |
Observed MW: | 48kDa |
This gene encodes a liver vitamin K-dependent glycoprotein that is synthesized in the liver and secreted into the plasma. The encoded protein plays a role in regulating blood coagulation by complexing with protein Z-dependent protease inhibitor to directly inhibit activated factor X at the phospholipid surface. Deficiencies in this protein are associated with an increased risk of ischemic arterial diseases and fetal loss. Mutations in this gene are the cause of protein Z deficiency. Alternate splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 8858 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |